Ingredient Spotlight

Grape seed extract in Neuro Serge

What is it?

Grape seed extract comes from the seeds of Vitis vinifera grapes and is typically standardized for proanthocyanidins, a class of polyphenols studied for antioxidant and anti-inflammatory activity.

What's been studied?

• Study type: Randomized, double-blind, placebo-controlled human trial
• Population: 96 healthy adults over age 55
• Intervention: 250 mg/day of a standardized grape extract (Cognigrape®)
• Duration: 84 days, with assessments at 14, 28, and 84 days
• Outcomes: Improvements across memory, visuospatial ability, language, and attention measures; some effects detected within 14 days and continuing through 84 days; selective attention improved within 90 minutes of the first dose
• Limitations: Single-center, industry-funded, studied only in healthy older adults, and not yet independently replicated

Source: Foods, 2024

What this means for Neuro Serge

Of the six ingredients in Neuro Serge, this trial reports the broadest set of positive cognitive outcomes. It's a well-designed single study with a verified dose (250 mg) — we have not confirmed whether Neuro Serge's capsule matches that amount.

What it does NOT prove

A single industry-funded trial, however well-designed, is not the same as a replicated body of evidence, and it does not establish what the finished Neuro Serge formula — six ingredients combined — does as a whole.