Evidence Library
Evidence library: every study, in detail
Each entry below documents one study we cite elsewhere on this site — its design, who it studied, what it measured, what it found, and where it falls short. All entries were fetched and checked to confirm they say what we cite them for.
| Study | Design | Population | Intervention | Outcome & finding | Limitations | Relevance to Neuro Serge |
|---|---|---|---|---|---|---|
| Olive leaf extract in mild Alzheimer's disease (GOLDEN Study), Neurology International, 2024 | Randomized controlled trial | 55 enrolled / 23 completed, ages 55–85, mild Alzheimer's disease | Olive-leaf-extract beverage + Mediterranean diet vs. diet alone, 6 months | MMSE: extract group ~0 change vs. −4.1 in controls (p=0.0135) | Small, high attrition, disease-specific population, beverage not capsule | Ingredient-level support for olive leaf; not tested as a capsule or in general adults |
| Green tea catechins and cognitive function, Molecules, 2020 | Randomized, placebo-controlled trial | 47 adults, ages 50–69 | 336.4 mg/day green tea catechins, 12 weeks | Improved working-memory response time; no change in overall memory/attention | Small, single-ethnicity sample, partial outcome only | Partial support for green tea; dose in Neuro Serge not confirmed to match |
| Standardized grape extract and cognition, Foods, 2024 | Randomized, double-blind, placebo-controlled trial | 96 healthy adults over 55 | 250 mg standardized grape extract/day, 84 days | Improved memory, visuospatial, language, and attention measures | Single-center, industry-funded, unreplicated | Promising but preliminary; one study, not a body of evidence |
| Cinnamon and cognitive function, systematic review, Nutritional Neuroscience, 2023 | Systematic review of 40 studies | 33 animal, 5 in-vitro, 2 clinical (neither measuring cognition) | N/A — review of existing literature | Reviewers report "0 clinical trials in humans looking at effects on cognitive function" | No human cognitive-outcome trials exist for cinnamon | Cassia cinnamon's cognitive rationale is currently animal/lab-only |
| Licorice and cognitive function, evidence summary, Alzheimer's Drug Discovery Foundation | Narrative evidence summary of clinical trials | 3 randomized clinical trials in people with cognitive decline | Licorice compounds (including glycyrrhizin-containing preparations) | No cognitive benefit found in the human trials reviewed | DGL specifically removes glycyrrhizin, the compound studied | Weakest evidence base of the six named ingredients |
| Antioxidant supplements: what you need to know, NCCIH (NIH) | Evidence summary of antioxidant supplement trials | General adult population across multiple trials | Various antioxidant supplements (vitamins C/E, beta-carotene, etc.) | "No evidence that antioxidant supplements have a positive impact" on most chronic disease outcomes studied | General antioxidant category, not specific to Neuro Serge's ingredients | General caution against assuming "antioxidant" implies proven benefit |
| Cognitive aging and training research, National Institute on Aging review, J. Gerontology: Series B, 2024 | Narrative review | General older-adult population | N/A — review of cognitive-training research field | Cognitive-training effects are real but "inconsistent, small-to-moderate," with sparse transfer beyond the trained task | Field-wide review, not ingredient-specific | General education context for cognitive health, not a Neuro Serge claim |
| Sleep and memory consolidation, review, Neuropsychologia, 2025 | Narrative review | N/A — review of sleep/memory literature | N/A | Sleep supports memory consolidation; the exact link to next-day learning remains an open question | Review-level, not a single trial | General education context; not a Neuro Serge claim |
| Exercise and cognitive function in older adults, systematic review & meta-analysis, Int. J. Environ. Res. Public Health, 2023 | Systematic review & meta-analysis of RCTs | 1,414 older adults across 21 RCTs | Aerobic and resistance training programs | Significant improvements across multiple standard cognitive test scores | Exercise-specific, not a supplement study | General education context; not a Neuro Serge claim |
Full inline links to each source are available on the homepage research section and the ingredients page.